DESPERATE Housewives was axed yesterday, meaning the upcoming eighth series will be the last.
In a statement, bosses of US network ABC said: "All good things must come to an end."
The series, set on Wisteria Lane and starring Eva Longoria, has suffered falling ratings.
Creator Marc Cherry has also been embroiled in a lawsuit.
Nicollette Sheridan, who played Edie Britt, is suing for £12million, claiming she was wrongfully sacked and that Marc slapped her.
The show has 120million global viewers, and airs on Channel 4.
Marcia Cross, who plays stuck-up Bree Van de Kamp, told fans on Twitter: "Thank you for all your love and support."