Katherine Heigl is due back on the Grey’s set at the end of the month, which means we probably won’t see Izzie again until late April. Coincidentally, that’s right around the time a very special patient will be checking into Seattle Grace: Alex’s brother! Sources confirm that Grey’s is currently casting the role of Karev’s estranged sibling. For those keeping score at home, this will be our first time meeting a member of Karev’s troubled clan. Look for bro to dredge up a lot of ugly family history, including that nasty business about daddy beating mommy.