Hollyoaks characters Mercedes Fisher (Jennifer Metcalfe) and Mitzeee (Rachel Shenton) are set to face off once again.
An upcoming storyline will reportedly see Mitzeee escape from prison in order to persuade Riley Costello (Rob Norbury) to run away with her, reports the Daily Star.
Mercedes is set to marry Riley for the second time, while she previously framed rival Mitzeee by stabbing herself and accusing her of carrying out the attack.
Riley decides to choose Mitzeee over Mercedes after she tracks him down to talk.
Meanwhile, Riley's father Carl returns to the village, increasing the tension between Riley and Mercedes following her affair with Carl before their previous wedding.
However, just before Mitzeee and Riley are able to run away together, his son Bobby goes missing, with Mercedes insisting on Mitzeee's involvement.
An insider said: "The entire village looks for Bobby, but Mercedes is quick to blame Mitzeee. She wastes no time naming her during the TV appeal.
"Riley is beside himself. He was planning to run away with Mitzeee so they could finally be together, and he can't help but wonder if she's taken him.
"The police are doing everything they can to locate both Mitzeee and Bobby and insist they all take part in the TV appeal.
"Even Carl agrees to put aside his differences to be there for his son and Mercedes. It's going to be one hell of an emotional week."
The storyline will begin on Channel 4 from September 28.
Rachel Shenton recently teased "big things" for Mitzeee on Hollyoaks Later, scheduled to air later this month.